发明名称 METHOD OF TREATING LARYNX PAPILLOMATOSIS
摘要 FIELD: medicine. ^ SUBSTANCE: invention relates to medicine and can be used for treatment of larynx papillomatosis. For this purpose treatment is performed in two stages. At the first stage larynx papillomas are ablated in endoscopic way under general anesthesia with application of CO2- laser. After decrease of post-operation edema at the second stage session of photodynamic therapy with application of 5-aminolevulinic acid chloride is carried out. 1.5-2 hours before the session 3.0 grams of preparation alasens are diluted in 200 ml of distilled water and are given to patient to drink in amount 30-50 mg/kg of body weight. After that, target zone is irradiated by laser with has power 250-300 mV/ cm2 by fibre-optic conductor with cylindrical disperser by means of helium-neon laser with wavelength 632.8 nm. Total energy dose is 150-180 J/cm2. Patient is placed into a darkened room until evening. ^ EFFECT: method makes it possible to achieve sanitation and eradication of small unremoved pieces of papillomas and long recurrence-free period. ^ 2 ex
申请公布号 RU2445027(C1) 申请公布日期 2012.03.20
申请号 RU20100130129 申请日期 2010.07.19
申请人 FGU "NKTS OTORINOLARINGOLOGII" FEDERAL'NOGO MEDIKO-BIOLOGICHESKOGO AGENTSTVA ROSSII 发明人 DAVUDOV KHASAN SHAKHMANOVICH;NAZHMUDINOV IBRAGIM ISMAILOVICH;AKOPJAN KAREN VALER'EVICH;GUSEJNOV ISMAIL GASANOVICH;KULIKOV IGOR' OLEGOVICH;DAVUDOVA BASHARAT KHASANOVNA;MAGOMEDOVA KAMILA MAGOMEDOVNA
分类号 A61B17/24;A61K31/195;A61N5/067;A61P11/04 主分类号 A61B17/24
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