| 发明名称 |
Imidazo[1,2-a]pyridine compounds as receptor tyrosine kinase inhibitors |
| 摘要 |
Compounds of Formula I: in which A, B, R1, R1a, R2, R3, R4, R5 R6, R7 and R8 have the meanings given in the specification, are receptor tyrosine inhibitors useful in the treatment of diseases mediated by class 3 and class 5 receptor tyrosine kinases. Particular compounds of this invention have also been found to be inhibitors of Pim-1. |
| 申请公布号 |
US8138181(B2) |
申请公布日期 |
2012.03.20 |
| 申请号 |
US20080593879 |
申请日期 |
2008.03.27 |
| 申请人 |
ALLEN SHELLEY;GRESCHUK JULIE MARIE;KALLAN NICHOLAS C.;MARMSAETER FREDRIK P.;MUNSON MARK C.;RIZZI JAMES P.;ROBINSON JOHN E.;SCHLACHTER STEPHEN T.;TOPALOV GEORGE T.;ZHAO QIAN;LYSSIKATOS JOSEPH P.;ARRAY BIOPHARMA INC. |
发明人 |
ALLEN SHELLEY;GRESCHUK JULIE MARIE;KALLAN NICHOLAS C.;MARMSAETER FREDRIK P.;MUNSON MARK C.;RIZZI JAMES P.;ROBINSON JOHN E.;SCHLACHTER STEPHEN T.;TOPALOV GEORGE T.;ZHAO QIAN;LYSSIKATOS JOSEPH P. |
| 分类号 |
A61K31/5386;A61K31/437;A61K31/506;A61P35/04;C07D401/14;C07D471/02;C07D498/08 |
主分类号 |
A61K31/5386 |
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