发明名称 HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND THE INHIBITION OF ANGIOGENESIS
摘要 Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutically compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
申请公布号 CA2553423(C) 申请公布日期 2012.03.20
申请号 CA20052553423 申请日期 2005.01.24
申请人 AMGEN INC. 发明人 POTASHMAN, MICHELE;KIM, TAE-SEONG;BELLON, STEVEN;BOOKER, SHON;CHENG, YUAN;KIM, JOSEPH L.;TASKER, ANDREW;XI, NING;XU, SHIMIN;HARMANGE, JEAN-CHRISTOPHE;BORG, GEORGE;WEISS, MATTHEW;HODOUS, BRIAN L.;GRACEFFA, RUSSELL;BUCKNER, WILLIAN H.;MASSE, CRAIG E.;CHOQUETTE, DEBORAH;MARTIN, MATTHEW W.;GERMAIN, JULIE;DIPIETRO, LUCIAN V.;CHAFFEE, STUART C.;NUNES, JOSEPH J.;BUCHANAN, JOHN L.;HABGOOD, GREGORY J.;MCGOWAN, DAVID C.;WHITTINGTON, DOUGLAS A.;PATEL, VINOD F.;LA, DANIEL
分类号 C07D215/22;A61K31/4709;A61K45/08;A61P9/00;A61P27/02;A61P35/00;C07D213/64;C07D213/81;C07D215/233;C07D215/38;C07D215/48;C07D215/54;C07D217/24;C07D237/34;C07D239/30;C07D239/34;C07D239/46;C07D239/84;C07D239/94;C07D401/12;C07D403/12;C07D405/12;C07D407/12;C07D409/12;C07D413/12;C07D417/12;C07D471/04;C07D487/04 主分类号 C07D215/22
代理机构 代理人
主权项
地址