发明名称 |
TREATMENT OF PARAOXONASE 1 (PON1) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO PON1 |
摘要 |
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Paraoxonase 1(PON1), in particular, by targeting natural antisense polynucleotides of Paraoxonase 1(PON1). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of PON1. |
申请公布号 |
KR20120026616(A) |
申请公布日期 |
2012.03.19 |
申请号 |
KR20127000707 |
申请日期 |
2010.06.16 |
申请人 |
OPKO CURNA, LLC |
发明人 |
COLLARD JOSEPH;KHORKOVA SHERMAN OLGA |
分类号 |
C12N15/63;A61K48/00;C12N15/113;C12Q1/68 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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