THERAPEUTIC AGENT FOR PAIN

摘要

[Problem] To provide a pharmaceutical product, especially a pharmaceutical composition which is useful for the treatment of pain. [Solution] The inventors have intensively studied using pain model animals for the purpose of providing a therapeutic agent for pain. As the results of the intensive studies, the inventors have found that a 11ß-hydroxydehydrogenase 1 (11ß-HSD1) inhibitor, especially a triazole compound which is characterized by having a ring group at the 3-position (or the 5-position) of a triazole ring has a good chronic pain improvement effect. Namely, a pharmaceutical composition which contains, as an active ingredient, a 11ß-HSD1 inhibitor, especially a triazole compound of the present invention is useful for the treatment of pain (especially, neuropathic pain and fibromyalgia syndrome).