DESIGN OF DRUG FORMULATION EXHIBITING STABLE ANGIOTENSIN II RECEPTOR ANTAGONISM

摘要

PROBLEM TO BE SOLVED: To provide a formulation in which a drug exhibiting an angiotensin II receptor antagonism, particularly, candesartan cilexetil is stabilized.

SOLUTION: Sodium stearyl fumarate is contained in the drug exhibiting the angiotensin II receptor antagonism, particularly, the candesartan cilexetil, thus decomposition of the active ingredients can be suppressed. As a result, contribution to stability is achieved.

COPYRIGHT: (C)2012,JPO&INPIT