| 摘要 |
<p>1306560 Acylamino - alkyl - benzenesulphonyl - (imino - imidazolidines) CIBAGEIGY AG 3 Sept 1970 [4 Sept 1969] 42105/70 Heading C2C [Also in Division A5] Novel, therapeutic compounds I (including salts thereof) where R 1 is is C 1 to C 6 alkyl, C 5 to C 8 cyclo alkyl, allyl or phenylalkyl of up to 9 C, R 2 is H, Me or Et, R 3 is a mononuclear heterocyclic group having 5 or 6 ring members and 1 or 2 hetero atoms (includes, e.g. pyrrolidinone) and m is 2 or 3 are made by reacting compounds II (also described as the dihydrochlorides and obtained by hydrolysing, e.g. corresponding acylamino compounds) with R 3 CO 2 H or a reactive functional derivative thereof. 1 - [p - (2 - Acetamidoethyl) - phenylsulphonyl] 2 - imino - 3 - cyclohexyl - imidazolidine is prepared by interacting 1-cyclohexyl-2-aminoimidazoline hydrochloride and p - (2 - acetamidoethyl) - benzene - sulphochloride (made by interacting chlorosulphonic acid and N-phenethylacetamide).</p> |
