发明名称 |
CILOSTAZOL COCRYSTALS AND COMPOSITIONS |
摘要 |
The invention relates to improvements of the physiochemical and/or the pharmaceutical properties of cilostazol. Disclosed herein are several new compositions and cocrystals of cilostazol, including: a 1:1 cilostazol gentisic acid cocrystal, a 1:1:1 cilostazol gentisic acid H20 cocrystal, a 1:1 cilostazol 4- hydroxybenzoic acid cocrystal, and a 1:1 cilostazol 2,4-dihydroxybenzoic acid cocrystal. The therapeutic methods and uses of these cilostazol cocrystals are described as well as therapeutic compositions containing them. |
申请公布号 |
WO2011158110(A3) |
申请公布日期 |
2012.03.15 |
申请号 |
WO2011IB01430 |
申请日期 |
2011.04.28 |
申请人 |
NUFORMIX LIMITED;HOLLAND, JOANNE;FRAMPTON, CHRISTOPHER;CHORLTON, ALAN;GOODING, DANIEL |
发明人 |
HOLLAND, JOANNE;FRAMPTON, CHRISTOPHER;CHORLTON, ALAN;GOODING, DANIEL |
分类号 |
A61K9/14;A61K31/47;A61P7/02;C07D401/12 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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