| 摘要 |
This invention relates to 2- (R2-thio) -10- [3- (4-R1--piperazin-1-yl) propyl]-10H-phenothiazines according to the general formula I, for treating a .beta.-amyloidopathy or .alpha.-synucleinopathy accompanied by a cerebral protein deposit and a reduced activity of the cerebral ABCC1-transporter. This invention also relates to a method for the diagnosis or prediagnosis of a .beta.-amyloidopathy or .alpha.-synucleopathy accompanied by a cerebral protein deposit and a reduced activity of the cerebral ABCC1-transporter, or for determining the risk of a proband suffering from such an illness, the proband already having accumulated substances transported by the cerebral ABCC1 transporter. |
