发明名称 COMPOSITION AND METHOD FOR INFERRING ANCESTRY
摘要 <P>PROBLEM TO BE SOLVED: To provide ancestry informative markers (AIMs) containing a single nucleotide polymorphism, and to provide a method for using a panel of AIMs for drawing an inference as to a trait of an individual. <P>SOLUTION: The method for inferring the trait of the individual includes following steps of: (a) contacting a nucleic acid containing sample of a test individual with an oligonucleotide probe that can detect nucleotide occurrences of single nucleotide polymorphisms (SNPs) of a panel of at least about ten AIMs wherein the population structure correlates with the trait; and (b) identifying, with a predetermined level of confidence, a population structure that correlates with the nucleotide occurrences of the AIMs in the test individual, wherein the population structure correlates with the trait, and inferring, with a predetermined level of confidence, the trait of the individual, which are biogeographical ancestry, pigmentation traits, drug responsiveness, or disease susceptibility of the individual. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012050432(A) 申请公布日期 2012.03.15
申请号 JP20110178621 申请日期 2011.08.17
申请人 DNAPRINT GENOMICS INC 发明人 FRUDAKIS TONY N;SHRIVER MARK D
分类号 C12Q1/68;A61K45/00;A61P3/06;A61P9/12;A61P13/08;A61P25/00;A61P25/16;A61P25/18;A61P25/32;A61P35/00;C12N15/09;G01N33/53;G06F19/14;G06F19/26 主分类号 C12Q1/68
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