摘要 |
<P>PROBLEM TO BE SOLVED: To provide ancestry informative markers (AIMs) containing a single nucleotide polymorphism, and to provide a method for using a panel of AIMs for drawing an inference as to a trait of an individual. <P>SOLUTION: The method for inferring the trait of the individual includes following steps of: (a) contacting a nucleic acid containing sample of a test individual with an oligonucleotide probe that can detect nucleotide occurrences of single nucleotide polymorphisms (SNPs) of a panel of at least about ten AIMs wherein the population structure correlates with the trait; and (b) identifying, with a predetermined level of confidence, a population structure that correlates with the nucleotide occurrences of the AIMs in the test individual, wherein the population structure correlates with the trait, and inferring, with a predetermined level of confidence, the trait of the individual, which are biogeographical ancestry, pigmentation traits, drug responsiveness, or disease susceptibility of the individual. <P>COPYRIGHT: (C)2012,JPO&INPIT |