Cell Sensor, And Monitoring Method Using Same For The Real-Time Monitoring Of Cell Capacitance

摘要

The present invention relates to a cell sensor for real-time monitoring of cell capacitance and a monitoring method using the same, and more particularly, to a cell sensor capable of monitoring an endocytosis process of a biomolecule through a cell surface receptor by attaching a cell between electrodes and then measuring in real time the capacitance between the electrodes over time, and a monitoring method using the same. A cell sensor for the real-time monitoring of cell capacitance according to an exemplary embodiment of the present invention includes a substrate; a first electrode and a second electrode that are formed on the substrate and spaced apart by a gap from each other, in which at least one or more cells are introduced to be attached onto the gap; and a passivation layer that is formed on each of the tops of the first electrode and the second electrode to prevent the cells from being attached onto the top of the first electrode and the second electrode. The cell sensor for the real-time monitoring of cell capacitance and the method for real-time monitoring of the cell condition using the same according to an exemplary embodiment of the present invention have the effect of being able to monitor an endocytosis process of a biomolecule through a cell surface receptor in real time, by attaching cells having a receptor for the particular biomolecule between electrodes and then measuring in real time the capacitance between the electrodes over time.