| 摘要 |
The disclosure provides methods and kits for detecting RNA interacting regions in genomic DNA. The methods involve introducing an RNA-degrading agent and a DNA-degrading agent into a nucleus and then detecting the one or more regions in the genomic DNA that are degraded by the DNA-degrading agent due to the presence of the RNA-degrading agent. The methods are useful, for diagnostic, prognostic, or other personalized medicine application where RNA interaction with one or more DNA regions is or may be correlated with a particular disease or condition. |
