发明名称 |
VERFAHREN ZUR VERWENDUNG VON DIKETOPIPERAZINEN UND ZUSAMMENSETZUNGEN, DIE DIESE ENTHALTEN |
摘要 |
<p>The invention provides a method of inhibiting the effects of platelet activating factor (PAF). For instance, a disease or condition mediated by PAF (particularly inflammation) can be treated or platelet aggregation can be inhibited. The invention also provides a method of inhibiting the production and/or release of interleukin 8 (IL-8) by cells. The effects of PAF and the production and/or release of IL-8 are inhibited according to the invention by a compound of the formula: wherein R1 and R2 are defined in the application, or a physiologically-acceptable salt thereof. The invention also provides pharmaceutical compositions comprising these compounds.</p> |
申请公布号 |
AT547101(T) |
申请公布日期 |
2012.03.15 |
申请号 |
AT20010957581T |
申请日期 |
2001.08.02 |
申请人 |
DMI BIOSCIENCES, INC. |
发明人 |
BAR-OR, DAVID;CURTIS, C.;RAO, NAGARAJA K. R.;THOMAS, GREG |
分类号 |
A61K31/495;A61K31/496;A61P7/02;A61P11/00;A61P11/06;A61P29/00;A61P31/00;A61P31/04;A61P37/08;A61P43/00;C07D241/04 |
主分类号 |
A61K31/495 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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