| 发明名称 |
MODULATING IRES-MEDIATED TRANSLATION |
| 摘要 |
Provided herein are compounds and methods for use in preventing or treating a viral infection mediated by a virus comprising an IRES-containing RNA molecule or cancer related to an increase or decrease in IRES-mediated translation of an RNA molecule. Also provided are methods of inhibiting or promoting IRES-mediated translation. Also provided are methods of screening for an agent that inhibits IRES-mediated translation.
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| 申请公布号 |
US2012065247(A1) |
申请公布日期 |
2012.03.15 |
| 申请号 |
US201013259503 |
申请日期 |
2010.03.26 |
| 申请人 |
THOMPSON SUNNIE R.;SCHWIEBERT ERIK MILLS;STREIFF JOHN H.;DISCOVERYBIOMED, INC.;THE UAB RESEARCH FOUNDATION |
发明人 |
THOMPSON SUNNIE R.;SCHWIEBERT ERIK MILLS;STREIFF JOHN H. |
| 分类号 |
A61K31/7088;A61K31/137;A61K31/167;A61K31/415;A61K31/426;A61K31/44;A61K31/4402;A61K31/4406;A61K31/713;A61P31/14;A61P31/20;A61P31/22;A61P35/00;C07C217/60;C07C235/56;C07D213/46;C07D213/75;C07D231/12;C07D277/46;C12N5/071;C12Q1/02;C12Q1/66;C12Q1/68;C12Q1/70 |
主分类号 |
A61K31/7088 |
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