发明名称 PROCESS FOR THE PRODUCTION OF HYALURONIC ACID IN ESCHERICHIA
摘要 The present invention relates to a method for the production of hyaluronic acid (HA) in Bacillus subtilis and Escherichia coli through plasmid vectors wherein the gene is under the control of strong promoter Pgrac, and a system for the selection of stable bacterial strains for the production of high levels of hyaluronic acid.
申请公布号 WO2012032154(A1) 申请公布日期 2012.03.15
申请号 WO2011EP65642 申请日期 2011.09.09
申请人 FIDIA FARMACEUTICI S.P.A.;CORSA, VINCENZA;NEGRO, ALESSANDRO;VACCARO, SUSANNA;MESSINA, LUCIANO 发明人 CORSA, VINCENZA;NEGRO, ALESSANDRO;VACCARO, SUSANNA;MESSINA, LUCIANO
分类号 C08B37/00;C12N9/10;C12N15/63;C12N15/75;C12P19/04;C12P19/26 主分类号 C08B37/00
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