SPLEEN TYROSINE KINASE AND BRAIN CANCERS

摘要

The present invention relates to a method for treating cancer, for instance brain tumors, in a subject by inhibiting spleen tyrosine kinase (Syk) by administering to said subject a therapeutically effective amount of a modulator of Syk, for example a specific antibody or a siRNA. The present invention also encompasses methods of diagnosing cancer by measuring levels of Syk, as well as method of targeted therapy using anti-Syk antibodies conjugated to therapeutic agents.