发明名称 METHOD FOR EFFICIENTLY INDUCING AND AMPLIFYING HEMATOPOIETIC STEM CELL
摘要 <P>PROBLEM TO BE SOLVED: To provide a means for efficiently amplifying hematopoietic stem cells and/or hematopoietic precursor cells, in particular, human hematopoietic stem cells and/or hematopoietic precursor cells. <P>SOLUTION: This method for amplifying hematopoietic cells and/or hematopoietic precursor cells is characterized by expressing a gene encoding a transcription factor Sox17. A cell culture obtained by the method for amplification, an amplifier for the hematopoietic stem cell and/or hematopoietic precursor cell made from an expression vector including the gene encoding the transcription factor Sox17, a composition for amplifying the hematopoietic stem cell and/or hematopoietic precursor cell containing the expression vector, and a reagent kit for amplification containing the expression vector as a reagent are provided. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012050357(A) 申请公布日期 2012.03.15
申请号 JP20100193828 申请日期 2010.08.31
申请人 CHIBA UNIV 发明人 IWAMA ATSUSHI;OSAWA MITSUJIRO;OSHIMA MOTOHIKO;KONUMA TAKAAKI
分类号 C12N5/10;C07K14/47;C12N5/0789;C12N15/09 主分类号 C12N5/10
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