COMPOSITIONS AND METHODS RELATED TO ATTENUATED STAPHYLOCOCCAL STRAINS
摘要
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve attenuated S. aureus strains having deletions in their genome, such as in the srtA and saeR regions.
申请公布号
WO2012034077(A2)
申请公布日期
2012.03.15
申请号
WO2011US51090
申请日期
2011.09.09
申请人
THE UNIVERSITY OF CHICAGO;SCHNEEWIND, OLAF;KIM, HYE-YOUNG;MISSIAKAS, DOMINIQUE, M.;KIM, HWAN KEUN