发明名称 |
Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates |
摘要 |
The present invention provides conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates. The conjugates as well as the polymeric reagents used to form the conjugates include at least one of each the following: an aromatic moiety comprising an ionizable hydrogen atom, a spacer moiety, and a water-soluble polymer. Methods of making polymeric reagents and conjugates, as well as methods for administering conjugates and compositions, are also provided. |
申请公布号 |
EP2279758(A3) |
申请公布日期 |
2012.03.14 |
申请号 |
EP20100184832 |
申请日期 |
2006.06.16 |
申请人 |
NEKTAR THERAPEUTICS |
发明人 |
BENTLEY, MICHAEL;CULBERTSON, SEAN;MCMANUS, SAMUEL |
分类号 |
A61K47/48;A61P3/10;C07C323/12;C07D213/70;C07K14/605 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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