| 摘要 |
<p>1505305 2 - Oxo - indoles and -quinolines OTSUKA PHARMACEUTICAL CO Ltd 23 June 1975 [24 June 1974 (2) 5 July 1974 (2) 16 Aug 1974 30 April 1975 (3) 15 May 1975 (5) 16 May 1975 (2) 2 June 1975] 26597/75 Heading C2C Novel compounds I: in which R 1 is H, C 1-4 alkyl, C 2-4 alkenyl, aralkyl or carboxyethyl, B is -CH 2 -, -CH 2 -CH 2 - or -CH=CH-, A is -CR 2 R 3 - (where R 2 and R 3 are H or C 1-4 alkyl) or -CH=CH-, R 4 is OR 5 (where R 5 is H, C 1-8 alkyl, cycloalkyl or aralkyl) or -NR 6 R 7 (where R 6 and R 7 are H, C 1-4 alkyl or aralkyl or may form together with the N atom a 5- or 6- membered heterocyclic group which may contain a further N, O or S atom, and m and n are each 0 or a positive integer, and m+n is no more than 11, and intermediates therefor, are prepared as shown in the following reaction scheme: Pharmaceutical compositions having platelet aggregation-inhibiting and antiphlogistic activity, for oral or parenteral administration, comprise a compound I together with a pharmaceutical carrier.</p> |
