发明名称 |
METHOD FOR THE DETERMINATION OF P BLOOD GROUPS |
摘要 |
<p>The invention relates to a method to discriminate between the P1 and P2 blood group alleles by the use of at least one nucleotide sequence being identical/homologous to at least part of the nucleotide sequences as shown in SEQ ID NO:1-6 or a nucleotide sequence showing at least 90% identity to any of SEQ ID NO:1-6 and wherein the difference is a cytosine (C) or thymidine (T) in position 129 as shown in SEQ ID NO:1, wherein C/C or C/T in the two alleles gives rise to the P1 phenotype and T/T to the P2 phenotype. Furthermore, zygosity for the P1 allele (i.e. C/C vs. C/T) also predicts the P1 and Pk antigen levels on man cells. The invention also relates to means to be used in said method including primers, probes and markers.</p> |
申请公布号 |
EP2427776(A1) |
申请公布日期 |
2012.03.14 |
申请号 |
EP20100772349 |
申请日期 |
2010.05.07 |
申请人 |
OLSSON, MARTIN L |
发明人 |
THURESSON, BRITT;OLSSON, MARTIN L. |
分类号 |
G01N33/80;C12N15/11;C12Q1/48;C12Q1/68 |
主分类号 |
G01N33/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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