发明名称 |
Oligonucleotide or its functional homologue, a composition comprising the same and a method of treating B cell neoplasm |
摘要 |
The invention provides an oligonucleotide with a sequence of SEQ ID NO: 1 or its functional homolgue, a composition comprising the same and a method for treating B cell neoplasm by using the oligonucleotide or its functional homologue or the composition comprising the oligonucleotide. The oligonulceotide induces the apoptosis of B cell neoplastic cells, up-regulates CD40 on B cell neoplastic cells and stimulates the production of IL-10 from B cell neoplastic cells. |
申请公布号 |
US8133874(B2) |
申请公布日期 |
2012.03.13 |
申请号 |
US20060914745 |
申请日期 |
2006.02.13 |
申请人 |
WANG LI-YING;BAO MU-SHENG;YU YONG-LI;CHANGCHUN HUAPU BIOTECHNOLOGY CO., LTD. |
发明人 |
WANG LI-YING;BAO MU-SHENG;YU YONG-LI |
分类号 |
A61K31/70;C07H21/02;C07H21/04;C12N15/117;C12Q1/68 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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