BICYCLIC CARBOHYDRATE COMPOUNDS USEFUL IN THE TREATMENT OF INFECTIONS CAUSED BY FLAVIVIRIDAE SP., SUCH AS HEPATITIS C AND BOVINE VIRAL DIARRHEA VIRUSES
摘要
We describe the use of bicyclic carbohydrates for the treatment of infections caused by Flaviviridae, especially hepatitis C virus infections, particularly the use of a pharmaceutically effective amount of a bicyclic carbohydrate having the formula: (see above formula) wherein: R1 is selected from the group consisting of -alkyl, -aryl and -benzyl; R2 and R3 are selected from the group consisting of -alkyl and -aryl; R4 is an -aryl; X is O; or a pharmaceutically active salt thereof in treating a Flaviviridae sp. infection.
申请公布号
CA2512713(C)
申请公布日期
2012.03.13
申请号
CA20032512713
申请日期
2003.12.22
申请人
KEMIN PHARMA EUROPE, B.V.B.A.
发明人
SAS, BENEDIKT;VAN HEMEL, JOHAN;VANDENKERCKHOVE, JAN;PEYS, ERIC;VAN DER EYCKEN, JOHAN;RUTTENS, BART;BALZARINI, JAN;DE CLERCQ, ERIK;NEYTS, JOHAN