PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING BRAIN DISEASE COMPRISING PHYTOSPHINGOSINE DERIVATIVE
摘要
PURPOSE: A pharmaceutical composition containing phytosphingosine is provided to suppress specific nSMase2 activity and to prevent or treat brain diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating brain diseases contains phytosphingosine derivative of chemical formula 1 as an active ingredient. The phytospingosine derivative I is D-lixo-phytospingosine of chemical formula 2 or D-arabino-phytospingosine of chemical formula 3.
申请公布号
KR20120023302(A)
申请公布日期
2012.03.13
申请号
KR20100085676
申请日期
2010.09.01
申请人
CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMY COOPERATIONFOUNDATION;SNU R&DB FOUNDATION
发明人
KIM, DAE KYONG;LEE, DONG HUN;AHN, KYONG HOON;KIM, SEOK KYUN;CHOI, JONG MIN;JI, JUNG EUN;WON, JONG HOON;KIM, SUNG HYUN;KIM, SANG HEE;LIM, CHAE MIN
