| 发明名称 |
Soluble heterodimeric cytokine receptor |
| 摘要 |
The present invention provides methods of treating psoriasis in a subject (i.e., psoriasis associated with a joint disease), by administering to the subject an effective dose of a composition comprising a soluble IL-22R/IL-20RB heterodimeric polypeptide, wherein the heterodimeric polypeptide comprises an IL-22R extracellular domain covalently linked to an IL-20RB extracellular domain. |
| 申请公布号 |
US8133487(B2) |
申请公布日期 |
2012.03.13 |
| 申请号 |
US20100695069 |
申请日期 |
2010.01.27 |
| 申请人 |
CHANDRASEKHER YASMIN A.;NOVAK JULIA E.;FOSTER DONALD C.;XU WENFENG;JASPERS STEPHEN R.;ZYMOGENETICS, INC. |
发明人 |
CHANDRASEKHER YASMIN A.;NOVAK JULIA E.;FOSTER DONALD C.;XU WENFENG;JASPERS STEPHEN R. |
| 分类号 |
A61K38/00;A61K39/00;A61P17/00;C07K14/715 |
主分类号 |
A61K38/00 |
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