| 发明名称 |
STABLE FORMULATIONS OF THIADIAZOLE DERIVATIIVE |
| 摘要 |
The present invention provides formulation parameters and manufacturing conditions for stable pharmaceutical compositions comprising N-{4-(2,2-dimethyl-propionyl)-(5R)-5-t(2-ethylamino-ethanesulfonylamino)-methyl]-5-phenyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl)-2,2-dimethyl-propionamide that minimize undesirable chiral conversion to the less active S enantiomeric form. |
| 申请公布号 |
UA97672(C2) |
申请公布日期 |
2012.03.12 |
| 申请号 |
UA20100000209 |
申请日期 |
2008.07.07 |
| 申请人 |
ELI LILLI AND COMPANY;KYOWA HAKKO KIRIN CO., LTD. |
发明人 |
KUSANO, HIROKO;MISHRA, DINESH SHUAMDEO;TASHIRO, YOSHIKAZU;WATANABE, YOSUKE;ZHUANG, HONG |
| 分类号 |
A61K9/19;A61K31/433 |
主分类号 |
A61K9/19 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
