SELF-ASSEMBLED MOLECULAR ARCHITECTURES HAVING SPECIFIC MORPHOLOGIES AND PREPARATION METHOD THEREOF

摘要

PURPOSE: A manufacturing method of a self-assembly of peptide is provided to form a self-assembly of peptide with a specific structure according to a hydrogen bond, and hydrophobicity between the surfaces of helix in solvophobic environment like water-soluble solvent. CONSTITUTION: A self-assembly of peptide is in chemical formula 1. In chemical formula 1, R1 is H or a protective group, R2 is OH, OR3, NR4R5 or a protective group, R3 is C1-6 alkyl, and C5-12 aryl or benzyl, R4 and R5 is respectively hydrogen, C1-6 alkyl, and C5-12 aryl or benzyl, and n is 2-20. A manufacturing method of a self-assembly of peptide comprises: a step of adding a compound in chemical formula 1 into solvent, and mixing the same; a step of forming precipitate of the manufactured solution by neglecting; a step of removing residue solvent by filtering the precipitate and cleaning the precipitate.