发明名称 NOVEL SALTS OF SUBSTITUTED 5-MEMBER AZACYCLE AND USE THEREOF IN TREATING PROTEIN AGEING RELATED DISEASES
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to 5-member azacyclic compounds of formula ^ , ^ where X denotes S; Y denotes O; Q denotes O; R1 denotes methyl or, together with R2, forms a 6-member aliphatic ring, R2 denotes methyl or, together with R1, forms a 6-member aliphatic ring; R3 denotes hydrogen; R4 denotes benzyl; Z- is a pharmaceutically acceptable acid radical. The invention also relates to a pharmaceutical composition, use of formula (I) compounds, which are active in destruction of advanced glycosylation end products (AGE), to obtain a medicinal agent and a method producing formula (I) compounds. ^ EFFECT: obtaining compounds of formula (I) which are active in destruction of advanced glycosylation end products (AGE). ^ 6 cl, 1 tbl, 6 ex
申请公布号 RU2444517(C2) 申请公布日期 2012.03.10
申请号 RU20080134899 申请日期 2007.01.29
申请人 BEJDZHING MOLIK'JUL SAJENS EHND TEKNOLODZHI KO., LTD 发明人 LI SUN;TSUJ KHAO;SJAO TSZJUN'KHAJ;CHZHUN VU;VAN LILI;CHEHN GAN
分类号 A61K31/426;A61K31/428;C07D277/22;C07D277/60 主分类号 A61K31/426
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