发明名称 |
NOVEL CHLORIN E6-FOLIC ACID CONJUGATE, PREPARATION METHOD THEREOF, AND A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER COMPRISING THE SAME |
摘要 |
The present invention relates to a novel chlorin e6-folic acid conjugate, a preparation method thereof, and a pharmaceutical composition for the treatment of cancer comprising the same, and more particularly, to a novel compound prepared by linking chlorin e6 to folic acid, which effectively produces singlet oxygen in various media and has much better tumor selectivity than the known porphyrin-based photosensitizers, thereby being used effectively in photodynamic therapy for malignant tumors, a preparation method thereof, and a pharmaceutical composition for photodynamic treatment of solid tumors comprising the compound. |
申请公布号 |
US2012059018(A1) |
申请公布日期 |
2012.03.08 |
申请号 |
US20090594186 |
申请日期 |
2009.04.29 |
申请人 |
PARK KYE SHIN;LEE EUN HEE;KIM HYO JUN;DIATECH KOREA CO., LTD. |
发明人 |
PARK KYE SHIN;LEE EUN HEE;KIM HYO JUN |
分类号 |
A61K31/519;A61P35/00;C07D487/22 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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