| 发明名称 |
FEEDBACK PRODRUG |
| 摘要 |
Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition are described. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enzyme.
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| 申请公布号 |
US2012058960(A1) |
申请公布日期 |
2012.03.08 |
| 申请号 |
US201113222495 |
申请日期 |
2011.08.31 |
| 申请人 |
BOONS GEERT-JAN;GUO JUN;UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. |
发明人 |
BOONS GEERT-JAN;GUO JUN |
| 分类号 |
A61K31/7034;A61P1/16;A61P3/10;A61P31/04;A61P31/10;A61P31/12;A61P35/00;C07H15/203 |
主分类号 |
A61K31/7034 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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