发明名称 |
Sialylated antigen-specific antibodies for treatment or prophylaxis of unwanted inflammatory immune reactions and methods of producing them |
摘要 |
The present invention is directed to a sialylated isolated antibody specific for an antigen selected from autoimmune antigens, allergens, MHC molecules or Rhesus factor D antigen, comprising an Fc-portion of IgG type, and exhibiting a sialic acid residue at the Fc-portion for use in treatment and/or prophylaxis of autoimmune disease, allergy, transplant rejection or Rhesus factor D reactivity and to methods of producing such an antibody.
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申请公布号 |
US2012058111(A1) |
申请公布日期 |
2012.03.08 |
申请号 |
US201013260727 |
申请日期 |
2010.03.26 |
申请人 |
EHLERS MARC;HESS CONSTANZE;LORENZ ALEXANDRA KATHARINA;WINKLER ANDRE |
发明人 |
EHLERS MARC;HESS CONSTANZE;LORENZ ALEXANDRA KATHARINA;WINKLER ANDRE |
分类号 |
A61K39/395;A61P37/06;C07K16/00;C07K16/18;C07K16/28;C12P21/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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