| 发明名称 |
LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS |
| 摘要 |
The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structures XIV or XVII. |
| 申请公布号 |
US2012058144(A1) |
申请公布日期 |
2012.03.08 |
| 申请号 |
US200913128363 |
申请日期 |
2009.11.10 |
| 申请人 |
MANOHARAN MUTHIAH;RAJEEV KALLANTHOTTATHIL G.;JAYARAMAN MUTHUSAMY;BUTLER DAVID;NARAYANANNAIR JAYAPRAKASH K.;CIUFOLINI MARCO A.;ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
MANOHARAN MUTHIAH;RAJEEV KALLANTHOTTATHIL G.;JAYARAMAN MUTHUSAMY;BUTLER DAVID;NARAYANANNAIR JAYAPRAKASH K.;CIUFOLINI MARCO A. |
| 分类号 |
A61K39/00;A61K31/713;A61K39/02;A61K39/12;A61K47/18;A61K47/22;A61K47/28;A61K48/00;A61P31/04;A61P31/12;A61P33/00;A61P35/00;A61P37/04;C07C217/52;C07C229/46;C07C291/04;C07D207/12;C07D211/46;C07D317/28;C12N5/00 |
主分类号 |
A61K39/00 |
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