| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a TNF-like cytokine involved in a pathological state. <P>SOLUTION: An isolated nucleic acid molecule containing polynucleotide with a sequence at least 95% homology with the following sequences is provided: (a) a sequence encoding neutrokine α polypeptide having a complete amino acid sequence in Fig.1; (b) a sequence encoding neutrokine α having a complete amino acid sequence encoded by cDNA clone included in deposition to ATCC on October 22nd 1996; (c) a sequence encoding neutrokine α polypeptide extracellular domain; (d) a sequence encoding neutrokine α polypeptide transmembrane domain; (e) a sequence encoding neutrokine α polypeptide intracellular domain; (f) a sequence encoding soluble neutrokine α polypeptide deleted of transmembrane domain; and (g) a sequence complementary to optional sequence of (a), (b), (c), (d), (e) or (f). <P>COPYRIGHT: (C)2012,JPO&INPIT |
