Humanized antibodies against ICAM-1, their production and uses

摘要

The invention provides humanized antibodies, for example, those that bind ICAM-1, methods of use and methods of producing the antibodies. Antibodies include sequences having a VH and VL domain selected from HumA, HumB, HumC, HumD, HumE, HumF, HumG, HumH, Huml, Hum40 and Hum 50. Figure 4 Protection against I MOI HRV15 -- Ms1 25 ++- Hum I --- Hum H -~ ~ -*Hum F 9 25 -A Hum D 0 - -9- Hum C 0 5 10 -+-Hum B -HumA uMolar