发明名称 |
METHOD FOR IMPROVEMENT OF DENDRITIC CELL MIGRATION AND OF CTL CYTOTOXICITY GENERATED WITH DENDRITIC CELLS |
摘要 |
PURPOSE: A method for enhancing cytotoxicity of cytotoxic T cells is provided to enhance mobility of dendritic cells to a second lymph organ and to induce maturation of novel dendritic cells. CONSTITUTION: A method for enhancing cytotoxicity of cytotoxic T cells comrises: a step of differentiating monocytes isolated from blood into immature dendritic cells; a step of treating antiviral cytokines, TLR activator, or mixture thereof to the immature dendritic cells to culture the immature dendritic cells; a step of treating a composition for enhancing mobility of dendritic cells to the immature dendritic cells to maturing the immature dendritic cells; and a step of adding IP-10(interferon-gamma inducible protein-10) to the matured dendritic cells.
|
申请公布号 |
KR101117186(B1) |
申请公布日期 |
2012.03.07 |
申请号 |
KR20110061540 |
申请日期 |
2011.06.24 |
申请人 |
INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY |
发明人 |
HONG, CHEOL YI;LEE, JE JUNG;KIM, MI HYUN |
分类号 |
C12N5/0784;C07K14/52;C12N5/02 |
主分类号 |
C12N5/0784 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|