发明名称 |
AUTOMATED DETECTION AND COUNTING OF BIOMOLECULES USING NANOPARTICLE PROBES |
摘要 |
<p>An apparatus and method for counting nanoparticle probes is disclosed. In one embodiment, quantum dot-tagged proteins on optically transparent membranes or slides are counted. The transparent membranes or slides are loaded onto a stage (e.g., an X-Y stage or X-Y-Z stage), which can automatically reposition the transparent membrane or slides for image capture at varying locations. A microscope can be used for providing a light source to fluoresce the nanocrystals and for providing the magnification needed for image capture. Once one or more images are captured, the nanoparticles can be automatically counted using post-processing software that maintains a total count across multiple images, if desired.</p> |
申请公布号 |
EP2425248(A2) |
申请公布日期 |
2012.03.07 |
申请号 |
EP20100770330 |
申请日期 |
2010.04.29 |
申请人 |
OREGON HEALTH & SCIENCE UNIVERSITY |
发明人 |
VU, TANIA, Q.;LONG, BRIAN, R.;SCHOLL, BENJAMIN, K. |
分类号 |
G01N33/533;G01N33/52;G01N33/561;G01N33/58 |
主分类号 |
G01N33/533 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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