| 发明名称 |
Treatment of neurological disorders by dsRNA administration |
| 摘要 |
The present invention relates to methods to treat neurological disorders comprising intrathecal injection of an effective amount of a double-stranded (ds) RNA into a subject in need, wherein the dsRNA inhibits the expression of a target gene and to pharmaceutical compositions useful for such treatment. |
| 申请公布号 |
US8129354(B2) |
申请公布日期 |
2012.03.06 |
| 申请号 |
US20070779098 |
申请日期 |
2007.07.17 |
| 申请人 |
DORN GABRIELE;GANJU PAMPOSH;HALL JONATHAN;HEMMINGS MARIA WANDA;WISHART WILLIAM LEONARD;NOVARTIS AG |
发明人 |
DORN GABRIELE;GANJU PAMPOSH;HALL JONATHAN;HEMMINGS MARIA WANDA;WISHART WILLIAM LEONARD |
| 分类号 |
A61K31/713;A61K38/00;A61P25/00;A61P25/28;C07H21/04;C12N15/113 |
主分类号 |
A61K31/713 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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