发明名称 |
Modified clostridial toxins with enhanced targeting capabilities for endogenous clostridial toxin receptor systems |
摘要 |
The specification discloses modified Clostridial toxins comprising a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and an enhanced Clostridial toxin binding domain; polynucleotide molecules encoding such modified Clostridial toxins; and method of producing such modified Clostridial toxins. |
申请公布号 |
US8128940(B2) |
申请公布日期 |
2012.03.06 |
申请号 |
US20060908349 |
申请日期 |
2006.03.14 |
申请人 |
STEWARD LANCE E.;FERNANDEZ-SALAS ESTER;FRANCIS JOSEPH;LI SHENGWEN;GILMORE MARCELLA A.;AOKI KEI R.;ALLERGAN, INC. |
发明人 |
STEWARD LANCE E.;FERNANDEZ-SALAS ESTER;FRANCIS JOSEPH;LI SHENGWEN;GILMORE MARCELLA A.;AOKI KEI R. |
分类号 |
C07K14/33;C07H21/04;C12N15/62 |
主分类号 |
C07K14/33 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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