发明名称 |
Indole derivatives as histamine 3 receptor inhibitors for the treatment of cognitive and sleep disorders, obesity and other CNS disorders |
摘要 |
This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial. |
申请公布号 |
US8129424(B2) |
申请公布日期 |
2012.03.06 |
申请号 |
US20100943659 |
申请日期 |
2010.11.10 |
申请人 |
BENNANI YOUSSEF L.;CAMPBELL MICHAEL G.;DASTRUP DAVID;HUCK EMILIE PORTER;ATHERSYS, INC. |
发明人 |
BENNANI YOUSSEF L.;CAMPBELL MICHAEL G.;DASTRUP DAVID;HUCK EMILIE PORTER |
分类号 |
A61K31/404;C07D209/12 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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