发明名称 |
Use of oxicam compounds |
摘要 |
The invention relates to the use of lornoxicam or analogues thereof which inhibit cyclo-oxygenase 1 and cyclo-oxygenase 2 (COX 1 and COX 2), cannot penetrate the blood-brain barrier under physiological conditions, and reduce the prostaglandin E2-induced induction of the amyloid-precursor-protein (APP), for producing a pharmaceutical composition for the treatment or prevention of Alzheimer's disease or arteriosclerosis. |
申请公布号 |
US8129370(B2) |
申请公布日期 |
2012.03.06 |
申请号 |
US20040558117 |
申请日期 |
2004.05.27 |
申请人 |
BINDER DIETER;BINDER, LEGAL REPRESENTATIVE EVA;DRITTE PATENTPORTFOLIO BETEILIGUNGSGESELLSCHAFT MBH & CO. KG |
发明人 |
BINDER DIETER;BINDER, LEGAL REPRESENTATIVE EVA |
分类号 |
A61K31/546;A61K31/4439;A61K31/54;A61P9/10;A61P25/28 |
主分类号 |
A61K31/546 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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