发明名称 |
Selective enzymatic esterification and solvolysis of epimeric vitamin D analog and separation of the epimers |
摘要 |
Provided is a method of selectively enzymatically esterifying or selectively enzymatically solvolyzing epimers of analogs of vitamin D having a stereogenic center at C-24 that has a free or esterified OH group. The metod can be used, for example, for separating mixed epimers of the vitamin D analog. |
申请公布号 |
US8129173(B2) |
申请公布日期 |
2012.03.06 |
申请号 |
US20030339226 |
申请日期 |
2003.01.09 |
申请人 |
SHAPIRO EVGENY;FISHMAN AYELET;EFFENBERGER REINHARD;MAYMON ASHER;SCHWARTZ ANCHEL;TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
SHAPIRO EVGENY;FISHMAN AYELET;EFFENBERGER REINHARD;MAYMON ASHER;SCHWARTZ ANCHEL |
分类号 |
C12P7/02;C12P7/62;C12N9/20;C12P7/18;C12P41/00 |
主分类号 |
C12P7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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