发明名称 Selective enzymatic esterification and solvolysis of epimeric vitamin D analog and separation of the epimers
摘要 Provided is a method of selectively enzymatically esterifying or selectively enzymatically solvolyzing epimers of analogs of vitamin D having a stereogenic center at C-24 that has a free or esterified OH group. The metod can be used, for example, for separating mixed epimers of the vitamin D analog.
申请公布号 US8129173(B2) 申请公布日期 2012.03.06
申请号 US20030339226 申请日期 2003.01.09
申请人 SHAPIRO EVGENY;FISHMAN AYELET;EFFENBERGER REINHARD;MAYMON ASHER;SCHWARTZ ANCHEL;TEVA PHARMACEUTICAL INDUSTRIES LTD. 发明人 SHAPIRO EVGENY;FISHMAN AYELET;EFFENBERGER REINHARD;MAYMON ASHER;SCHWARTZ ANCHEL
分类号 C12P7/02;C12P7/62;C12N9/20;C12P7/18;C12P41/00 主分类号 C12P7/02
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