| 摘要 |
PURPOSE: A composition containing Geranium nepalense extract is provided to promote chondrogenesis and to protect and regenerate bone tissue or cartilage. CONSTITUTION: A pharmaceutical composition for suppressing osteoclast differentiation contains Sorbus commixta extract, Geranium nepalense extract, and a mixture thereof as active ingredients. A pharmaceutical composition for regenerating or protecting bone or cartilage contains the extract of Sorbus commixta, Geranium nepalense, or mixture thereof as active ingredients. The extract is isolated using water, anhydrous or hydrous low alcohol of 1-4 carbon atoms, a mixture solvent of the low alcohol and water, acetone, ethyl acetate, chloroform, butyl acetate, butylenes glycol, propylene glycol, dichloromethane, hexane, diethyl ether, or mixture thereof.
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