发明名称 HUMANIZED ANTI-NGF ANTIBODIES
摘要 <p>A humanized anti-NGF antibody or a fragment thereof which maintains binding activity to NGF, wherein the humanized anti-NGF antibody comprises, (a) a VH region having a first CDR comprising the amino acid sequence GFSLTNNNVNW, a second CDR comprising the amino acid sequence GVWAGGATDYNSALKS, and a third CDR comprising the amino acid sequence DGGYSSSTLYAMDA; and (b) a VL region having a first CDR comrising the amino acid sequence RASEDIYNALA, a second CDR comprising the amino acid sequence HT, and a third CDR sequence comprising the amino acid sequence QHYFHYPRT.</p>
申请公布号 PT2138512(E) 申请公布日期 2012.03.05
申请号 PT20090008366T 申请日期 2004.12.23
申请人 ABBOTT RESEARCH B.V. 发明人 ANTONIO CATTANEO;SONIA COVACEUSZACH;DORIANO LAMBA
分类号 C07K16/00;C07K16/22;C07K16/28;C07K16/46;G06F19/00;G06F19/16 主分类号 C07K16/00
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