发明名称 |
Treatment Of Chronic Obstructive Pulmonary Disease With Phosphodiesterase-4 Inhibitor |
摘要 |
Disclosed is a method of treatment of chronic obstructive pulmonary disease associated with chronic bronchitis in a patient at risk of exacerbations. The method includes administering to a patient with a history of chronic obstructive pulmonary disease associated with chronic bronchitis and at risk of exacerbations, a maintenance dose of 500 micrograms per day of roflumilast. Also disclosed is a method of increasing pre-bronchodilator FEV1 or post-bronchodilator FEV1 in such a patient, and increasing pre-bronchodilator FVC or post-bronchodilator FVC in such a patient. Further disclosed is a method of reducing the rate of exacerbations in such a patient. |
申请公布号 |
US2012052122(A1) |
申请公布日期 |
2012.03.01 |
申请号 |
US201113216936 |
申请日期 |
2011.08.24 |
申请人 |
BREDENBROEKER DIRK;NYCOMED GMBH |
发明人 |
BREDENBROEKER DIRK |
分类号 |
A61K9/28;A61K31/44;A61K31/537;A61P11/00;A61P11/08 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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