INHIBITION OF TUMOR GROWTH AND METASTASIS BY N5 GENE

摘要

The present invention concerns method for treating pancreatic and ovarian cancers in a subject. These methods employ compositions comprising the N5 gene product, p84N5 and include nucleic acids and proteins/peptides or polypeptides encoding p84N5 or portions thereof. The invention also concerns prognostic wherein the levels of expression of p84N5 have been correlated to sensitivity to radiation treatments and/or chemotherapeutic agents. Therefore, the invention also concerns methods for prescribing a specific therapeutic regimen comprising specific radiation and chemotherapy doses and adjustments in such doses based on the individual patients p84N5 expression levels.