OPTICALLY ACTIVE NOVEL ANTI-INFLAMMATORY COMPOUND AND METHOD FOR PRODUCING SAME
摘要
<p>The present invention addresses the problem of providing an optical isomer having the stronger activity of a compound that is stronger than conventional steroids or NSAIDs. The problem was resolved by discovering that an optical isomer of a particular dihydroxy body (17,18-dihydroxy eicosapentaenoic acid (17,18-diHEPE), or the like) of docosahexaenoic acid and eicosapentaenoic acid that was not heretofore known has neutrophil suppression activity. The optical isomer of the compound is a substance that has not been conventionally known. Consequently, the present invention provides utility as a new therapeutic agent.</p>
申请公布号
WO2012026106(A1)
申请公布日期
2012.03.01
申请号
WO2011JP04657
申请日期
2011.08.22
申请人
THE UNIVERSITY OF TOKYO;ARITA, MAKOTO;INOUE, MASAYUKI;URABE, DAISUKE;ARAI, HIROYUKI;MASUDA, KOUJI