| 发明名称 |
BACE 2 INHIBITORS |
| 摘要 |
The present invention relates to N-1-Benzyl-2-hydroxy-3-(hetero)arylamino-propyl)-isophthalamides of formula I having BACE2 inhibitory activity and their use as therapeutically active substances, their manufacture and pharmaceutical compositions. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. type 2 diabetes.
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| 申请公布号 |
US2012053200(A1) |
申请公布日期 |
2012.03.01 |
| 申请号 |
US201113215273 |
申请日期 |
2011.08.23 |
| 申请人 |
MAUSER HARALD;NETTEKOVEN MATTHIAS;SCHMITT SEBASTIEN |
发明人 |
MAUSER HARALD;NETTEKOVEN MATTHIAS;SCHMITT SEBASTIEN |
| 分类号 |
A61K31/439;A61K31/40;A61K31/4025;A61K31/4155;A61K31/426;A61K31/427;A61K31/4402;A61K31/4439;A61P3/10;C07D207/06;C07D207/08;C07D213/56;C07D221/22;C07D277/30;C07D409/04;C07D409/14;C07D417/04;C07D417/12 |
主分类号 |
A61K31/439 |
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