ANTI-EGFR ANTIBODIES

摘要

Monoclonal antibodies that bind and inhibit activation of epidermal growth factor receptor related member EGFRL858R/T790M are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of EGFRL858R/T790M, EGFRvIII or wild-type EGFR amplification.