SOLUBLE LYMPHOTOXIN &bgr; RECEPTOR FOR THERAPEUTIC AGENT FOR TREATMENT OF IMMUNOLOGICAL DISEASE, ANTI-LYMPHOTOXIN RECEPTOR, AND LIGAND ANTIBODY

摘要

PROBLEM TO BE SOLVED: To solve the problem in the conventional technology so as to treat a lymphocyte-mediated immunological disease or, more specifically, inhibit a Th1 cell-mediated immunologic response.

SOLUTION: There is provided a method for treating or lowering the advancing, severity, or influence of the immunological disease in an animal, which includes a process of dosing a therapeutically effective amount of LT-β-R blocking agent and a pharmaceutical composition containing an acceptable carrier. In one embodiment, the LT-β-R blocking agent is selected from a group of antibodies to soluble lymphotoxinβreceptor, LT-βreceptor, and surface LT ligand.

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