| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a novel compound which has angiotensin II receptor antagonism and PPARγ activating action, and is useful as a preventing and/or therapeutic agent for hypertension, heart disease, angina pectoris, cerebrovascular disorder, cerebral circulation disorder, ischemia nature peripheral circulatory failure, kidney disease, arteriosclerosis, inflammatory disease, 2 type diabetes, diabetic complication, insulin resistance syndrome, syndrome X, metabolic syndrome, and high insulinemia. <P>SOLUTION: A 3-(5-ethoxypyrimidin-2-yl)pyrimidine-4(3H)-one derivative, a salt thereof or a solvate thereof, and a pharmaceutical composition containing the same are disclosed. <P>COPYRIGHT: (C)2012,JPO&INPIT |
